Thesis Supervisor 1 Retno Aulia Vinarti, S.Kom., M.Kom., Ph.D.
Thesis Supervisor 2 Renny Pradina, S.T., M.T.
App and Design by Muhammad Rasyad Caesarardhi
Data processed and summarized using Bringing Order to Abstractive Summarization paper
Original data provided by Atlas of Human Infectious Diseases
| Subjects | Quick Description (AI) |
|---|---|
DiseaseDisease - Original textMalaria, Plasmodium ovale | Malaria, Plasmodium ovale |
ClassificationClassification - Original textICD-9 084.3; ICD-10 B53.0 | ICD-9 084.3; ICD-10 B53.0 |
Syndromes and synonymsSyndromes and synonyms - Original textmalaria, paludism, tropical fever. | malaria, paludism, tropical fever. |
AgentAgent - Original textPlasmodium ovale, an intacellular protozoan parasite in the Phylum Apicomplexa. Phylogenetically, P. ovale clusters with other Plasmodium species affecting simian primates. | plasmodium ovale |
ReservoirReservoir - Original textHumans and possibly other primates (chimpanzees). Evidence of naturally occurring P. ovale in chimpanzees has been reported. | humans and possibly other primates (chimpanzees). |
VectorVector - Original textFemale mosquito of the genus Anopheles (see Anopheles map). | female mosquito of the genus anopheles |
TransmissionTransmission - Original textBy mosquito bite (Anopheles spp.). | by mosquito bite (anopheles spp.) |
CycleCycle - Original textInfective sporozoites are inoculated by the bite of anopheles mosquitoes and through the bloodstream and lymphatics reach the liver where they differentiate into tissue schizonts that release merozoites, or to a dormant stage (hypnozoite) that can become active after months or years, causing relapse. Merozoites released from liver infect erythrocytes that develop to schizonts, rupture and release merozoites that will infect new erythrocytes (this cycle takes 48 hours). Some merozoites develop into gametocytes that are able to infect mosquitoes during a blood meal. | infective sporozoites are inoculated by the bite of anopheles mosquitoes and through the bloodstream and lymphatics reach the liver. some merozoites develop into gametocytes that are able to infect mosquitoes during a blood meal. |
Incubation periodIncubation period - Original text12 to 20 days, up to to several months | 12 to 20 days, up to to several months |
Clinical findingsClinical findings - Original textAcute febrile illness with chills, sweats, nausea, headache, and vomiting. Usually does not last longer than 2 weeks. | acute febrile illness with chills, sweats, nausea, headache, and vomiting. |
Diagnostic testsDiagnostic tests - Original textMicroscopy of Giemsa-stained blood film; differentiation from P. vivax can be difficult and result in misidentification; parasite load is generally low and may be undetectable by light microscopy; in regions where P. falciparum/P. vivax predominate, P. ovale is frequently overlooked; parasitemia is present for about 2 weeks; PCR. | microscopy of giemsa-stained blood film; pcr. |
TherapyTherapy - Original textNeed to treat both P. ovale blood and liver stage with chloroquine (blood stage) and primaquine (liver stage). | need to treat both p. ovale blood and liver stage with chloroquine (blood stage) and primaquine (liver stage). |
PreventionPrevention - Original textVector control; mosquito repellent; insecticidetreated bed nets; treatment of infected humans. | vector control; mosquito repellent; insecticidetreated bed nets; treatment of infected humans. |
EpidemiologyEpidemiology - Original textP. ovale initally was thought to be limited to Sub-Saharan Africa, Papua New Guinea, eastern Indonesia, and the Philippines. It is actually more widely distributed, and is reported in the Middle East, the Indian Subcontinent, and various parts of Southeast Asia. P. ovale has not yet been reported in South America. In general, P. ovale is relatively uncommon, though in West Africa prevalences above 10% are observed. Also, infections are most common in children <10 years. There is likely underreporting due to underdiagnosis. Due to the short duration of parasitemia and low parasite loads, P. ovale is regularly ‘missed’ in cross-sectional surveys. | p. ovale initally was thought to be limited to sub-saharan africa, papua new guinea, eastern indonesia, and the philippines. it is actually more widely distributed, and is reported in the middle east, the indian subcontinent, and various parts of southeast asia. |
CommunicabilityCommunicability - Original textNaN | - |
Prepatent periodPrepatent period - Original textNaN | - |