Thesis Supervisor 1 Retno Aulia Vinarti, S.Kom., M.Kom., Ph.D.
Thesis Supervisor 2 Renny Pradina, S.T., M.T.
App and Design by Muhammad Rasyad Caesarardhi
Data processed and summarized using Bringing Order to Abstractive Summarization paper
Original data provided by Atlas of Human Infectious Diseases
| Subjects | Quick Description (AI) |
|---|---|
DiseaseDisease - Original textDengue | Dengue |
ClassificationClassification - Original textDengue fever (DF): ICD-9 061, ICD-10 A90; Dengue hemorrhagic fever/Dengue shock syndrome (DHF/ DSS): Dengue fever (DF): ICD-9 061, ICD-10 A90; Dengue hemorrhagic fever/Dengue shock syndrome (DHF/ | Dengue fever (DF): ICD-9 061, ICD-10 A90; Dengue hemorrhagic fever/Dengue shock syndrome (DHF/ DSS): Dengue fever (DF): ICD-9 061, ICD-10 A90; Dengue hemorrhagic fever/Dengue shock syndrome (DHF/ |
Syndromes and synonymsSyndromes and synonyms - Original textBreakbone fever. | breakbone fever. |
AgentAgent - Original textDengue virus (DENV) is an enveloped RNA virus, genus Flavivirus in the family Flaviviridae. There are four antigenically related, but distinct, dengue virus serotypes (DEN-1, DEN-2, DEN-3, and DEN-4), all of which can cause DF/DHF. | dengue virus (denv) is an enveloped rna virus, genus flavivirus in the family flaviviridae |
ReservoirReservoir - Original textHumans; forest monkeys in West Africa and Southeast Asia. | humans; forest monkeys in west africa and southeast asia |
VectorVector - Original textMost commonly, the urban container-breeding, daybitingmosquitoesAedes aegypti and Ae. albopictus; in Polynesia, Ae. scutellaris complex spp.; in Malaysia, Ae. nivaeus complex spp., in West Africa, Ae. furcifer-taylori complex spp., and recently in Europe by Ae. albopictus (see Aedes map). | most commonly, the urban container-breeding, daybitingmosquitoesaedes aegypti and ae. albopictus |
TransmissionTransmission - Original textBy mosquito bite. | by mosquito bite. |
CycleCycle - Original textHuman–mosquito–human around housing; monkey–mosquito–monkey and monkey–mosquito–human in the forests of West Africa and Malaysia. Human viremia lasts 3–5 days since onset of symptoms; the mosquito can transmit 8–12 days after taking a viremic blood meal, depending on the ambient temperature. | human–mosquito–human around housing; monkey–mosquitito–monkey and monkey–Mosquito-human in the forests of west africa and malaysia. |
Incubation periodIncubation period - Original text3–14 days (usually 4–7 days). | 3–14 days (usually 4–7 days). |
Clinical findingsClinical findings - Original textSudden onset of fever lasting 2–7 days, sometimes biphasic, severe headache, myalgia, arthralgia, retro-orbital pain, anorexia, nausea, vomiting and a maculopapular rash (not easily seen on dark skin). Most cases recover. Minor occurrence of petechiae, epistaxis, or gingival bleeding may be seen. Serious hemorrhagic manifestations, like a severe drop in blood platelets, indicate dengue hemorrhagic fever (DHF), that can progress to dengue shock syndrome (DSS) and death. Infection with any serotype results in lasting homologous immunity, but little cross-immunity to other serotypes. Cross-immunity may exacerbate, rather than diminish, disease severity when infected with a new serotype; DHF leading to DSS can occur as a secondary infection with a different serotype, but DHF/DSS has also been reported in primary infections. CFR for DHF is up to 20%, for untreated DSS up to 50%, and 1–2% if correctly treated. | severe headache, severe headache, myalgia, arthralgia, retro-orbital pain, anorexia, nausea, vomiting and a maculopapular rash (not easily seen on dark skin). most cases recover. minor occurrence of petechiae, epistaxis, or gingival bleeding may be seen. |
Diagnostic testsDiagnostic tests - Original textIgM capture ELISA; NS1 antigen test; RTPCR of blood or tissue; virus isolation in mosquitoes or mosquito cell culture with identification by IFA. | igm capture elisa; ns1 antigen test; rtpcr of blood or tissue; virus isolation in mosquitoes or mosquito cell culture; ifa. |
TherapyTherapy - Original textSupportive, including rehydration. Avoid aspirin because of potential hemorrhage. | supportive, including rehydration. avoid aspirin |
PreventionPrevention - Original textRemoval of breeding sites in any type of container that holds water (e.g. vase, tire). Larviciding standing water, adulticiding with non-persistent insecticides. Personal protection with suitable clothing, mosquito repellents, nets, and screens. | removal of breeding sites in any type of container that holds water (e.g. vase, tire). larviciding standing water, adulticiding with non-persistent insecticides. personal protection with suitable clothing, mosquito repellents, nets, and screens. |
EpidemiologyEpidemiology - Original textThe global dengue distribution follows vector presence and introduction of the virus, and occurs basically between the 10 C isotherms. Autochthonous dengue fever cases appeared in Europe for the first time in 2010, north of 10 C isotherm and likely transmitted by Ae. albopictus (see Aedes agypti and Aedes albopictus map). There is strong seasonality, correlated with the rainy season, which produces a marked increase in vectors because more mosquito-breeding sites become available then. Two, 3 or all 4 serotypes may occur concurrently. DHF/DSS in many countries is most often seen in children suffering a secondary infection with a different serotype. Incidence rates of up to 3% have been seen in dengue naõve populations such as are found in some Pacific islands. | the global dengue distribution follows vector presence and introduction of the virus, and occurs basically between the 10 c isotherms. there is strong seasonality, correlated with the rainy season, which produces a marked increase in vectors |
CommunicabilityCommunicability - Original textNaN | - |
Prepatent periodPrepatent period - Original textNaN | - |